Constitutively Active SMAD2/3 Are Broad-Scope Potentiators of Transcription-Factor-Mediated Cellular Reprogramming

Reprogramming of cellular identity using exogenous expression of transcription factors (TFs) is a powerful and exciting tool for tissue engineering, disease modeling, and regenerative medicine. However, generation of desired cell types using this approach is often plagued by inefficiency, slow conve...

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Detalles Bibliográficos
Autores principales: Ruetz, Tyson, Pfisterer, Ulrich, Di Stefano, Bruno, Ashmore, James, Beniazza, Meryam, Tian, Tian V., Kaemena, Daniel F., Tosti, Luca, Tan, Wenfang, Manning, Jonathan R., Chantzoura, Eleni, Ottosson, Daniella Rylander, Collombet, Samuel, Johnsson, Anna, Cohen, Erez, Yusa, Kosuke, Linnarsson, Sten, Graf, Thomas, Parmar, Malin, Kaji, Keisuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732323/
https://www.ncbi.nlm.nih.gov/pubmed/29174331
http://dx.doi.org/10.1016/j.stem.2017.10.013

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