EBI2 receptor regulates myelin development and inhibits LPC-induced demyelination

BACKGROUND: The G protein-coupled receptor EBI2 (Epstein-Barr virus-induced gene 2) is activated by 7α, 25-dihydroxycholesterol (7α25HC) and plays a role in T cell-dependant antibody response and B cell migration. Abnormal EBI2 signaling is implicated in a range of autoimmune disorders; however, its...

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Detalles Bibliográficos
Autores principales: Rutkowska, Aleksandra, Sailer, Andreas W., Dev, Kumlesh K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732472/
https://www.ncbi.nlm.nih.gov/pubmed/29246262
http://dx.doi.org/10.1186/s12974-017-1025-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732472/
https://www.ncbi.nlm.nih.gov/pubmed/29246262
http://dx.doi.org/10.1186/s12974-017-1025-0

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