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Linking physiologically-based pharmacokinetic and genome-scale metabolic networks to understand estradiol biology

BACKGROUND: Estrogen is a vital hormone that regulates many biological functions within the body. These include roles in the development of the secondary sexual organs in both sexes, plus uterine angiogenesis and proliferation during the menstrual cycle and pregnancy in women. The varied biological...

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Detalles Bibliográficos
Autores principales:	Sier, Joanna H., Thumser, Alfred E., Plant, Nick J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732473/ https://www.ncbi.nlm.nih.gov/pubmed/29246152 http://dx.doi.org/10.1186/s12918-017-0520-3

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