Etiogenic factors present in the cerebrospinal fluid from amyotrophic lateral sclerosis patients induce predominantly pro-inflammatory responses in microglia

BACKGROUND: Microglial cell-associated neuroinflammation is considered as a potential contributor to the pathophysiology of sporadic amyotrophic lateral sclerosis. However, the specific role of microglia in the disease pathogenesis remains to be elucidated. METHODS: We studied the activation profile...

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Detalles Bibliográficos
Autores principales: Mishra, Pooja-Shree, Vijayalakshmi, K., Nalini, A., Sathyaprabha, T. N., Kramer, B. W., Alladi, Phalguni Anand, Raju, T. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732516/
https://www.ncbi.nlm.nih.gov/pubmed/29246232
http://dx.doi.org/10.1186/s12974-017-1028-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732516/
https://www.ncbi.nlm.nih.gov/pubmed/29246232
http://dx.doi.org/10.1186/s12974-017-1028-x

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