Polyvinylpyrrolidone-coated gold nanoparticles inhibit endothelial cell viability, proliferation, and ERK1/2 phosphorylation and reduce the magnitude of endothelial-independent dilator responses in isolated aortic vessels

BACKGROUND: Gold nanoparticles (AuNPs) demonstrate clinical potential for drug delivery and imaging diagnostics. As AuNPs aggregate in physiological fluids, polymer-surface modifications are utilized to allow their stabilization and enhance their retention time in blood. However, the impact of AuNPs...

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Detalles Bibliográficos
Autores principales: Mohamed, Teba, Matou-Nasri, Sabine, Farooq, Asima, Whitehead, Debra, Azzawi, May
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732551/
https://www.ncbi.nlm.nih.gov/pubmed/29263670
http://dx.doi.org/10.2147/IJN.S133093

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