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Necrosis of the thumb after inadvertent injection of diclofenac in the radial artery: a case report

Inadvertent intra-arterial drug injection occurs rarely, but it can cause very serious clinical complications, and thus, awareness of inadvertent intra-arterial drug injection is needed. The complications mainly result from iatrogenic reasons and can occur because of vascular variations in the arter...

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Autores principales: Shon, Hyun-Chul, Park, Ji-Kang, Kang, Sang-Woo, Yang, Jae-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732554/
https://www.ncbi.nlm.nih.gov/pubmed/29263695
http://dx.doi.org/10.2147/JPR.S150306
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author Shon, Hyun-Chul
Park, Ji-Kang
Kang, Sang-Woo
Yang, Jae-Young
author_facet Shon, Hyun-Chul
Park, Ji-Kang
Kang, Sang-Woo
Yang, Jae-Young
author_sort Shon, Hyun-Chul
collection PubMed
description Inadvertent intra-arterial drug injection occurs rarely, but it can cause very serious clinical complications, and thus, awareness of inadvertent intra-arterial drug injection is needed. The complications mainly result from iatrogenic reasons and can occur because of vascular variations in the arteries, under circumstances where normal intravenous injection is difficult, or in drug abusers who perform self-injection. The adverse effect associated with intra-arterial drug injection is serious and may lead to necrosis, requiring amputation of the affected extremity, infection, pseudoaneurysm, rhabdomyolysis, compartment syndrome, and permanent disability. However, the etiology of such adverse effects has not been clearly identified and treatment methods have not yet been established. We encountered a patient who developed necrosis of the thumb after an inadvertent injection of diclofenac sodium in the radial artery due to variations in the forearm arteries. Here, we report the prevention and treatment of, and precautions against, the dangers of intra-arterial drug injection.
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spelling pubmed-57325542017-12-20 Necrosis of the thumb after inadvertent injection of diclofenac in the radial artery: a case report Shon, Hyun-Chul Park, Ji-Kang Kang, Sang-Woo Yang, Jae-Young J Pain Res Case Report Inadvertent intra-arterial drug injection occurs rarely, but it can cause very serious clinical complications, and thus, awareness of inadvertent intra-arterial drug injection is needed. The complications mainly result from iatrogenic reasons and can occur because of vascular variations in the arteries, under circumstances where normal intravenous injection is difficult, or in drug abusers who perform self-injection. The adverse effect associated with intra-arterial drug injection is serious and may lead to necrosis, requiring amputation of the affected extremity, infection, pseudoaneurysm, rhabdomyolysis, compartment syndrome, and permanent disability. However, the etiology of such adverse effects has not been clearly identified and treatment methods have not yet been established. We encountered a patient who developed necrosis of the thumb after an inadvertent injection of diclofenac sodium in the radial artery due to variations in the forearm arteries. Here, we report the prevention and treatment of, and precautions against, the dangers of intra-arterial drug injection. Dove Medical Press 2017-12-13 /pmc/articles/PMC5732554/ /pubmed/29263695 http://dx.doi.org/10.2147/JPR.S150306 Text en © 2017 Shon et al. This work is published and licensed by Dove Medical Press Limited The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.
spellingShingle Case Report
Shon, Hyun-Chul
Park, Ji-Kang
Kang, Sang-Woo
Yang, Jae-Young
Necrosis of the thumb after inadvertent injection of diclofenac in the radial artery: a case report
title Necrosis of the thumb after inadvertent injection of diclofenac in the radial artery: a case report
title_full Necrosis of the thumb after inadvertent injection of diclofenac in the radial artery: a case report
title_fullStr Necrosis of the thumb after inadvertent injection of diclofenac in the radial artery: a case report
title_full_unstemmed Necrosis of the thumb after inadvertent injection of diclofenac in the radial artery: a case report
title_short Necrosis of the thumb after inadvertent injection of diclofenac in the radial artery: a case report
title_sort necrosis of the thumb after inadvertent injection of diclofenac in the radial artery: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732554/
https://www.ncbi.nlm.nih.gov/pubmed/29263695
http://dx.doi.org/10.2147/JPR.S150306
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