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Increased Hyperalgesia and Proinflammatory Cytokines in the Spinal Cord and Dorsal Root Ganglion After Surgery and/or Fentanyl Administration in Rats

Perioperative fentanyl has been reported to induce hyperalgesia and increase postoperative pain. In this study, we tried to investigate behavioral hyperalgesia, the expression of proinflammatory cytokines, such as interleukin-1β (IL-1β), interleukin-6 (IL-6), and tumor necrosis factor-α (TNF-α), and...

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Detalles Bibliográficos
Autores principales: Chang, Lu, Ye, Fang, Luo, Quehua, Tao, Yuanxiang, Shu, Haihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732642/
https://www.ncbi.nlm.nih.gov/pubmed/29135586
http://dx.doi.org/10.1213/ANE.0000000000002601