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GUCY2C maintains intestinal LGR5(+) stem cells by opposing ER stress

Long-lived multipotent stem cells (ISCs) at the base of intestinal crypts adjust their phenotypes to accommodate normal maintenance and post-injury regeneration of the epithelium. Their long life, lineage plasticity, and proliferative potential underlie the necessity for tight homeostatic regulation...

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Detalles Bibliográficos
Autores principales:	Kraft, Crystal L., Rappaport, Jeffrey A., Snook, Adam E., Pattison, Amanda M., Lynch, John P., Waldman, Scott A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732700/ https://www.ncbi.nlm.nih.gov/pubmed/29262534 http://dx.doi.org/10.18632/oncotarget.22084

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