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Reprogramming of leukemic cell metabolism through the naphthoquinonic compound Quambalarine B
Abnormalities in cancer metabolism represent potential targets for cancer therapy. We have recently identified a natural compound Quambalarine B (QB), which inhibits proliferation of several leukemic cell lines followed by cell death. We have predicted ubiquinone binding sites of mitochondrial respi...
Autores principales: | Vališ, Karel, Grobárová, Valéria, Hernychová, Lucie, Bugáňová, Martina, Kavan, Daniel, Kalous, Martin, Černý, Jiří, Stodůlková, Eva, Kuzma, Marek, Flieger, Miroslav, Černý, Jan, Novák, Petr |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732718/ https://www.ncbi.nlm.nih.gov/pubmed/29262552 http://dx.doi.org/10.18632/oncotarget.21663 |
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