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Deletion or inhibition of soluble epoxide hydrolase protects against brain damage and reduces microglia-mediated neuroinflammation in traumatic brain injury

Traumatic brain injury (TBI) induces a series of inflammatory processes that contribute to neuronal damage. The present study investigated the involvement of soluble epoxide hydrolase (sEH) in neuroinflammation and brain damage in mouse TBI and in microglial cultures. The effects of genetic deletion...

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Detalles Bibliográficos
Autores principales: Hung, Tai-Ho, Shyue, Song-Kun, Wu, Chun-Hu, Chen, Chien-Cheng, Lin, Chao-Chang, Chang, Che-Feng, Chen, Szu-Fu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732724/
https://www.ncbi.nlm.nih.gov/pubmed/29262558
http://dx.doi.org/10.18632/oncotarget.21139