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Deletion or inhibition of soluble epoxide hydrolase protects against brain damage and reduces microglia-mediated neuroinflammation in traumatic brain injury
Traumatic brain injury (TBI) induces a series of inflammatory processes that contribute to neuronal damage. The present study investigated the involvement of soluble epoxide hydrolase (sEH) in neuroinflammation and brain damage in mouse TBI and in microglial cultures. The effects of genetic deletion...
Autores principales: | Hung, Tai-Ho, Shyue, Song-Kun, Wu, Chun-Hu, Chen, Chien-Cheng, Lin, Chao-Chang, Chang, Che-Feng, Chen, Szu-Fu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732724/ https://www.ncbi.nlm.nih.gov/pubmed/29262558 http://dx.doi.org/10.18632/oncotarget.21139 |
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