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Characterization of epithelial-mesenchymal transition intermediate/hybrid phenotypes associated to resistance to EGFR inhibitors in non-small cell lung cancer cell lines
Increasing evidence points to a key role played by epithelial-mesenchymal transition (EMT) in cancer progression and drug resistance. In this study, we used wet and in silico approaches to investigate whether EMT phenotypes are associated to resistance to target therapy in a non-small cell lung canc...
Autores principales: | Fustaino, Valentina, Presutti, Dario, Colombo, Teresa, Cardinali, Beatrice, Papoff, Giuliana, Brandi, Rossella, Bertolazzi, Paola, Felici, Giovanni, Ruberti, Giovina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732732/ https://www.ncbi.nlm.nih.gov/pubmed/29262566 http://dx.doi.org/10.18632/oncotarget.21132 |
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