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Reversion of resistance to oxaliplatin by inhibition of p38 MAPK in colorectal cancer cell lines: involvement of the calpain / Nox1 pathway

Oxaliplatin is a major treatment for metastatic colorectal cancer, however its effectiveness is greatly diminished by the development of resistances. Our previous work has shown that oxaliplatin efficacy depends on the reactive oxygen species (ROS) produced by Nox1. In this report, we investigated N...

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Detalles Bibliográficos
Autores principales: Chocry, Mathieu, Leloup, Ludovic, Kovacic, Hervé
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732761/
https://www.ncbi.nlm.nih.gov/pubmed/29262595
http://dx.doi.org/10.18632/oncotarget.21780

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