Recurrent somatic mutations of PRKAR1A in isolated cardiac myxoma

BACKGROUND: Cardiac myxomas are benign tumors that commonly arise within the left atria. Familial cardiac myxomas are a part of Carney Complex (CNC), an autosomal dominant multiple neoplasia syndrome caused by germline mutations in PRKAR1A. Seven percent of cardiac myxomas are associated with CNC. T...

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Detalles Bibliográficos
Autores principales: He, Jian, Sun, Mingju, Li, Enyou, Hou, Yingyong, Shepard, Matthew J., Chen, Di, Pacak, Karel, Wang, Changsong, Guo, Lei, Zhuang, Zhengping, Liu, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732779/
https://www.ncbi.nlm.nih.gov/pubmed/29262613
http://dx.doi.org/10.18632/oncotarget.21916

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