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Mansouramycin C kills cancer cells through reactive oxygen species production mediated by opening of mitochondrial permeability transition pore

Cancer is one of the deadliest diseases in the world and the search for novel anticancer agents is urgently required. Marine-derived isoquinolinequinones have exhibited promising anticancer activities. However, the exact mechanisms of cytotoxic activities of these isoquinolinequinones are poorly cha...

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Detalles Bibliográficos
Autores principales:	Kuang, Shan, Liu, Ge, Cao, Ruobing, Zhang, Linlin, Yu, Qiang, Sun, Chaomin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732787/ https://www.ncbi.nlm.nih.gov/pubmed/29262621 http://dx.doi.org/10.18632/oncotarget.22004

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