Cholesterol overload in the liver aggravates oxidative stress-mediated DNA damage and accelerates hepatocarcinogenesis

Primary liver cancers represent the second leading cause of cancer-related deaths worldwide. Diverse etiological factors include chronic viral hepatitis, aflatoxin and alcohol exposure as well as aberrant liver lipid overload. Cholesterol has been identified as a key inducer of metabolic impairment,...

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Detalles Bibliográficos
Autores principales: Enríquez-Cortina, Cristina, Bello-Monroy, Oscar, Rosales-Cruz, Patricia, Souza, Verónica, Miranda, Roxana U., Toledo-Pérez, Rafael, Luna-López, Armando, Simoni-Nieves, Arturo, Hernández-Pando, Rogelio, Gutiérrez-Ruiz, María Concepción, Calvisi, Diego F., Marquardt, Jens U., Bucio, Leticia, Gomez-Quiroz, Luis Enrique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732793/
https://www.ncbi.nlm.nih.gov/pubmed/29262627
http://dx.doi.org/10.18632/oncotarget.22024

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