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Advances in the understanding and management of T-cell prolymphocytic leukemia

T-prolymphocytic leukemia (T-PLL) is a rare T-cell neoplasm with an aggressive clinical course. Leukemic T-cells exhibit a post-thymic T-cell phenotype (Tdt(−), CD1a(−), CD5(+), CD2(+) and CD7(+)) and are generally CD4(+)/CD8(−), but CD4(+)/CD8(+) or CD8(+)/CD4(−) T-PLL have also been reported. The...

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Detalles Bibliográficos
Autores principales: Laribi, Kamel, Lemaire, Pierre, Sandrini, Jeremy, Baugier de Materre, Alix
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732835/
https://www.ncbi.nlm.nih.gov/pubmed/29262669
http://dx.doi.org/10.18632/oncotarget.22272