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Immunization with Live Attenuated Leishmania donovani Centrin(−/−) Parasites Is Efficacious in Asymptomatic Infection

Currently, there is no vaccine against visceral leishmaniasis (VL). Toward developing an effective vaccine, we have reported extensively on the immunogenicity of live attenuated LdCentrin(−/−) mutants in naive animal models. In VL endemic areas, asymptomatic carriers outnumber symptomatic cases of V...

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Detalles Bibliográficos
Autores principales: Ismail, Nevien, Kaul, Amit, Bhattacharya, Parna, Gannavaram, Sreenivas, Nakhasi, Hira L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732910/
https://www.ncbi.nlm.nih.gov/pubmed/29312315
http://dx.doi.org/10.3389/fimmu.2017.01788