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Immunization with Live Attenuated Leishmania donovani Centrin(−/−) Parasites Is Efficacious in Asymptomatic Infection
Currently, there is no vaccine against visceral leishmaniasis (VL). Toward developing an effective vaccine, we have reported extensively on the immunogenicity of live attenuated LdCentrin(−/−) mutants in naive animal models. In VL endemic areas, asymptomatic carriers outnumber symptomatic cases of V...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732910/ https://www.ncbi.nlm.nih.gov/pubmed/29312315 http://dx.doi.org/10.3389/fimmu.2017.01788 |