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Relevance of the NLRP3 Inflammasome in the Pathogenesis of Chronic Liver Disease

Inflammation is a common characteristic of chronic liver disease (CLD). Inflammasomes are multiprotein complexes that can sense and recognize various exogenous and endogenous danger signals, eventually activating interleukin (IL)-1β and IL-18. The sensor component of the inflammasome system is a nuc...

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Detalles Bibliográficos
Autores principales: Wu, Xiaoqin, Dong, Lei, Lin, Xianhe, Li, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732938/
https://www.ncbi.nlm.nih.gov/pubmed/29312290
http://dx.doi.org/10.3389/fimmu.2017.01728