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Murine Precision-Cut Kidney Slices as an ex vivo Model to Evaluate the Role of Transforming Growth Factor-β1 Signaling in the Onset of Renal Fibrosis

Renal fibrosis is characterized by progressive accumulation of extracellular matrix (ECM) proteins, resulting in loss of organ function and eventually requiring renal replacement therapy. Unfortunately, no efficacious treatment options are available to halt renal fibrosis and translational models to...

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Detalles Bibliográficos
Autores principales:	Stribos, Elisabeth G. D., Seelen, Marc A., van Goor, Harry, Olinga, Peter, Mutsaers, Henricus A. M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732966/ https://www.ncbi.nlm.nih.gov/pubmed/29311960 http://dx.doi.org/10.3389/fphys.2017.01026

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