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GHK Peptide Inhibits Bleomycin-Induced Pulmonary Fibrosis in Mice by Suppressing TGFβ1/Smad-Mediated Epithelial-to-Mesenchymal Transition
Objective: Idiopathic pulmonary fibrosis is an irreversible and progressive fibrotic lung disease that leads to declines in pulmonary function and, eventually, respiratory failure and has no effective treatment. Gly-His-Lys (GHK) is a tripeptide involved in the processes of tissue regeneration and w...
Autores principales: | Zhou, Xiao-Ming, Wang, Gui-Liang, Wang, Xiao-Bo, Liu, Li, Zhang, Qin, Yin, Yan, Wang, Qiu-Yue, Kang, Jian, Hou, Gang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5733019/ https://www.ncbi.nlm.nih.gov/pubmed/29311918 http://dx.doi.org/10.3389/fphar.2017.00904 |
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