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Overexpression of Human-Derived DNMT3A Induced Intergenerational Inheritance of Active DNA Methylation Changes in Rat Sperm

DNA methylation is the major focus of studies on paternal epigenetic inheritance in mammals, but most previous studies about inheritable DNA methylation changes are passively induced by environmental factors. However, it is unclear whether the active changes mediated by variations in DNA methyltrans...

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Detalles Bibliográficos
Autores principales:	Zheng, Xiaoguo, Li, Zhenhua, Wang, Guishuan, Li, Zhengzheng, Liang, Ajuan, Wang, Hanshu, Dai, Yubing, Huang, Xingxu, Chen, Xuejin, Ma, Yuanwu, Sun, Fei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5733082/ https://www.ncbi.nlm.nih.gov/pubmed/29312436 http://dx.doi.org/10.3389/fgene.2017.00207

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