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Fertility-sparing surgery in advanced stage malignant ovarian germ cell tumor: a case report
BACKGROUND: Malignant ovarian germ cell tumor is a rare type of disease, which generally has a good prognosis due to the high chemosensitivity of this type of tumor. Fertility preservation is an important issue because malignant ovarian germ cell tumor commonly affects young women. Although conserva...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5733088/ https://www.ncbi.nlm.nih.gov/pubmed/29248013 http://dx.doi.org/10.1186/s13256-017-1516-8 |
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author | Ghalleb, Montassar Bouzaiene, Hatem Slim, Skander Hadiji, Achraf Hechiche, Monia Ben Hassouna, Jamel Rahal, Khaled |
author_facet | Ghalleb, Montassar Bouzaiene, Hatem Slim, Skander Hadiji, Achraf Hechiche, Monia Ben Hassouna, Jamel Rahal, Khaled |
author_sort | Ghalleb, Montassar |
collection | PubMed |
description | BACKGROUND: Malignant ovarian germ cell tumor is a rare type of disease, which generally has a good prognosis due to the high chemosensitivity of this type of tumor. Fertility preservation is an important issue because malignant ovarian germ cell tumor commonly affects young women. Although conservation is the standard for early stage, it becomes more debatable as the disease progresses to more advanced stages. Aim: Report the case of a patient with an International Federation of Gynecology and Obstetrics Stage IIIc malignant ovarian germ cell tumor, who had conservative surgery and chemotherapy with a good fertility outcome. CASE PRESENTATION: A 23-year-old North African woman with a left malignant ovarian germ cell tumor stage IIIc was treated by left adnexectomy and omentectomy followed by chemotherapy. A 15-year follow-up showed no signs of relapse, and she completed three full-term natural pregnancies. CONCLUSIONS: Malignant ovarian germ cell tumor is a rare ovarian tumor with a good prognosis. It is usually associated with a good fertility outcome in early stages. However, due to the rarity of the disease in advanced stages, the fertility outcome for this group of patients is not clear. This lack of data surrounding advanced stages points to the need for a meta-analysis of all published cases. |
format | Online Article Text |
id | pubmed-5733088 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-57330882017-12-21 Fertility-sparing surgery in advanced stage malignant ovarian germ cell tumor: a case report Ghalleb, Montassar Bouzaiene, Hatem Slim, Skander Hadiji, Achraf Hechiche, Monia Ben Hassouna, Jamel Rahal, Khaled J Med Case Rep Case Report BACKGROUND: Malignant ovarian germ cell tumor is a rare type of disease, which generally has a good prognosis due to the high chemosensitivity of this type of tumor. Fertility preservation is an important issue because malignant ovarian germ cell tumor commonly affects young women. Although conservation is the standard for early stage, it becomes more debatable as the disease progresses to more advanced stages. Aim: Report the case of a patient with an International Federation of Gynecology and Obstetrics Stage IIIc malignant ovarian germ cell tumor, who had conservative surgery and chemotherapy with a good fertility outcome. CASE PRESENTATION: A 23-year-old North African woman with a left malignant ovarian germ cell tumor stage IIIc was treated by left adnexectomy and omentectomy followed by chemotherapy. A 15-year follow-up showed no signs of relapse, and she completed three full-term natural pregnancies. CONCLUSIONS: Malignant ovarian germ cell tumor is a rare ovarian tumor with a good prognosis. It is usually associated with a good fertility outcome in early stages. However, due to the rarity of the disease in advanced stages, the fertility outcome for this group of patients is not clear. This lack of data surrounding advanced stages points to the need for a meta-analysis of all published cases. BioMed Central 2017-12-17 /pmc/articles/PMC5733088/ /pubmed/29248013 http://dx.doi.org/10.1186/s13256-017-1516-8 Text en © The Author(s). 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Case Report Ghalleb, Montassar Bouzaiene, Hatem Slim, Skander Hadiji, Achraf Hechiche, Monia Ben Hassouna, Jamel Rahal, Khaled Fertility-sparing surgery in advanced stage malignant ovarian germ cell tumor: a case report |
title | Fertility-sparing surgery in advanced stage malignant ovarian germ cell tumor: a case report |
title_full | Fertility-sparing surgery in advanced stage malignant ovarian germ cell tumor: a case report |
title_fullStr | Fertility-sparing surgery in advanced stage malignant ovarian germ cell tumor: a case report |
title_full_unstemmed | Fertility-sparing surgery in advanced stage malignant ovarian germ cell tumor: a case report |
title_short | Fertility-sparing surgery in advanced stage malignant ovarian germ cell tumor: a case report |
title_sort | fertility-sparing surgery in advanced stage malignant ovarian germ cell tumor: a case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5733088/ https://www.ncbi.nlm.nih.gov/pubmed/29248013 http://dx.doi.org/10.1186/s13256-017-1516-8 |
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