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Heterologous Secretory Expression and Characterization of Dimerized Bone Morphogenetic Protein 2 in Bacillus subtilis

Recombinant human Bone Morphogenetic Protein 2 (rhBMP2) has important applications in the spine fusion and ortho/maxillofacial surgeries. Here we first report the secretory expression of biological active dimerized rhBMP2 from Bacillus subtilis system. The mature domain of BMP2 gene was amplified fr...

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Detalles Bibliográficos
Autores principales:	Hanif, Muhammad Umair, Gul, Roquyya, Hanif, Muhammad Imran, Hashmi, Abid Ali
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5733156/ https://www.ncbi.nlm.nih.gov/pubmed/29333457 http://dx.doi.org/10.1155/2017/9350537

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