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Phosphorylated α-Synuclein-Copper Complex Formation in the Pathogenesis of Parkinson's Disease

Parkinson's disease is the second most important neurodegenerative disorder worldwide. It is characterized by the presence of Lewy bodies, which are mainly composed of α-synuclein and ubiquitin-bound proteins. Both the ubiquitin proteasome system (UPS) and autophagy-lysosomal pathway (ALS) are...

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Detalles Bibliográficos
Autores principales: Castillo-Gonzalez, Juan Antonio, Loera-Arias, Maria De Jesus, Saucedo-Cardenas, Odila, Montes-de-Oca-Luna, Roberto, Garcia-Garcia, Aracely, Rodriguez-Rocha, Humberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5733240/
https://www.ncbi.nlm.nih.gov/pubmed/29333317
http://dx.doi.org/10.1155/2017/9164754