Cargando…

The Absence of NOD1 Enhances Killing of Aspergillus fumigatus Through Modulation of Dectin-1 Expression

One of the major life-threatening infections for which severely immunocompromised patients are at risk is invasive aspergillosis (IA). Despite the current treatment options, the increasing antifungal resistance and poor outcome highlight the need for novel therapeutic strategies to improve outcome o...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gresnigt, Mark S., Jaeger, Martin, Subbarao Malireddi, R. K., Rasid, Orhan, Jouvion, Grégory, Fitting, Catherine, Melchers, Willem J. G., Kanneganti, Thirumala-Devi, Carvalho, Agostinho, Ibrahim-Granet, Oumaima, van de Veerdonk, Frank L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5733348/ https://www.ncbi.nlm.nih.gov/pubmed/29326692 http://dx.doi.org/10.3389/fimmu.2017.01777

Ejemplares similares

Genetic deficiency of NOD2 confers resistance to invasive aspergillosis
por: Gresnigt, Mark S., et al.
Publicado: (2018)

Infection-Mediated Priming of Phagocytes Protects against Lethal Secondary Aspergillus fumigatus Challenge
por: Savers, Amélie, et al.
Publicado: (2016)

Reducing hypoxia and inflammation during invasive pulmonary aspergillosis by targeting the Interleukin-1 receptor
por: Gresnigt, Mark S., et al.
Publicado: (2016)

Role of type I interferons in inflammasome activation, cell death, and disease during microbial infection
por: Malireddi, R. K. Subbarao, et al.
Publicado: (2013)

The PANoptosome: A Deadly Protein Complex Driving Pyroptosis, Apoptosis, and Necroptosis (PANoptosis)
por: Samir, Parimal, et al.
Publicado: (2020)

ZBP1 and TAK1: Master Regulators of NLRP3 Inflammasome/Pyroptosis, Apoptosis, and Necroptosis (PAN-optosis)
por: Malireddi, R. K. Subbarao, et al.
Publicado: (2019)

Role of inflammasomes/pyroptosis and PANoptosis during fungal infection
por: Briard, Benoit, et al.
Publicado: (2021)

Role of the Nlrp3 Inflammasome in Microbial Infection
por: Anand, Paras K., et al.
Publicado: (2011)

PANoptosis components, regulation, and implications
por: Malireddi, R.K. Subbarao, et al.
Publicado: (2020)

Integrated stress response restricts macrophage necroptosis
por: Place, David E, et al.
Publicado: (2021)

The Multifaceted Role of T-Helper Responses in Host Defense against Aspergillus fumigatus
por: Dewi, Intan M. W., et al.
Publicado: (2017)

IL-10 engages macrophages to shift Th17 cytokine dependency and pathogenicity during T cell-mediated colitis
por: Li, Bofeng, et al.
Publicado: (2015)

Chronic TLR Stimulation Controls NLRP3 Inflammasome Activation through IL-10 Mediated Regulation of NLRP3 Expression and Caspase-8 Activation
por: Gurung, Prajwal, et al.
Publicado: (2015)

Osteoclast fusion and bone loss are restricted by interferon inducible guanylate binding proteins
por: Place, David E., et al.
Publicado: (2021)

Hierarchical Cell Death Program Disrupts the Intracellular Niche Required for Burkholderia thailandensis Pathogenesis
por: Place, David E., et al.
Publicado: (2021)

ZBP1/DAI ubiquitination and sensing of influenza vRNPs activate programmed cell death
por: Kesavardhana, Sannula, et al.
Publicado: (2017)

Pancancer transcriptomic profiling identifies key PANoptosis markers as therapeutic targets for oncology
por: Mall, Raghvendra, et al.
Publicado: (2022)

ZBP1 Drives IAV-Induced NLRP3 Inflammasome Activation and Lytic Cell Death, PANoptosis, Independent of the Necroptosis Executioner MLKL
por: Malireddi, R. K. Subbarao, et al.
Publicado: (2023)

The crucial role of the Aspergillus fumigatus siderophore system in interaction with alveolar macrophages
por: Schrettl, Markus, et al.
Publicado: (2010)

Targeting zinc homeostasis to combat Aspergillus fumigatus infections
por: Vicentefranqueira, Rocío, et al.
Publicado: (2015)

The Beta-Glucan Receptor Dectin-1 Recognizes Specific Morphologies of Aspergillus fumigatus
por: Steele, Chad, et al.
Publicado: (2005)

Distinct Roles for Dectin-1 and TLR4 in the Pathogenesis of Aspergillus fumigatus Keratitis
por: Leal, Sixto M., et al.
Publicado: (2010)

Fungal Chitin Dampens Inflammation through IL-10 Induction Mediated by NOD2 and TLR9 Activation
por: Wagener, Jeanette, et al.
Publicado: (2014)

NLRP6 Negatively Regulates Innate Immunity and Host Defense Against Bacterial Pathogens
por: Anand, Paras K., et al.
Publicado: (2012)

TAK1 restricts spontaneous NLRP3 activation and cell death to control myeloid proliferation
por: Malireddi, R.K. Subbarao, et al.
Publicado: (2018)

Inflammatory cell death, PANoptosis, screen identifies host factors in coronavirus innate immune response as therapeutic targets
por: Malireddi, R. K. Subbarao, et al.
Publicado: (2023)

The C-Type Lectin Receptor Dectin-2 Is a Receptor for Aspergillus fumigatus Galactomannan
por: Reedy, Jennifer L., et al.
Publicado: (2023)

Phagocytosis of Aspergillus fumigatus conidia by primary nasal epithelial cells in vitro
por: Botterel, Françoise, et al.
Publicado: (2008)

The transcription factor IRF1 and guanylate-binding proteins target AIM2 inflammasome activation by Francisella infection
por: Man, Si Ming, et al.
Publicado: (2015)

Determining distinct roles of IL-1α through generation of an IL-1α knockout mouse with no defect in IL-1β expression
por: Malireddi, R.K. Subbarao, et al.
Publicado: (2022)

Galactosaminogalactan activates the inflammasome to provide host protection
por: Briard, Benoit, et al.
Publicado: (2020)

Role of Dectin-1 in the innate immune response of rat corneal epithelial cells to Aspergillus fumigatus
por: Xu, Qiang, et al.
Publicado: (2015)

PU.1 is involved in the immune response to Aspergillus fumigatus through upregulating Dectin-1 expression
por: Wang, Min, et al.
Publicado: (2016)

Toll-like receptor 2 induced cytotoxic T-lymphocyte-associated protein 4 regulates Aspergillus-induced regulatory T-cells with pro-inflammatory characteristics
por: Raijmakers, Ruud P. H., et al.
Publicado: (2017)

Whole-genome CRISPR screen identifies RAVER1 as a key regulator of RIPK1-mediated inflammatory cell death, PANoptosis
por: Malireddi, R.K. Subbarao, et al.
Publicado: (2023)

Murine Borrelia arthritis is highly dependent on ASC and caspase-1, but independent of NLRP3
por: Oosting, Marije, et al.
Publicado: (2012)

Innate immune priming in the absence of TAK1 drives RIPK1 kinase activity–independent pyroptosis, apoptosis, necroptosis, and inflammatory disease
por: Malireddi, R.K. Subbarao, et al.
Publicado: (2019)

The dectin-1/inflammasome pathway is responsible for the induction of protective T-helper 17 responses that discriminate between yeasts and hyphae of Candida albicans
por: Cheng, Shih-Chin, et al.
Publicado: (2011)

Cathepsin B modulates lysosomal biogenesis and host defense against Francisella novicida infection
por: Qi, Xiaopeng, et al.
Publicado: (2016)

Critical role of caspase-8–mediated IL-1 signaling in promoting Th2 responses during asthma pathogenesis
por: Qi, Xiaopeng, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_n2uh1mlopd6g5mfrumn8jj6i5u