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Lysophosphatidylcholine Regulates Sexual Stage Differentiation in the Human Malaria Parasite Plasmodium falciparum

Transmission represents a population bottleneck in the Plasmodium life cycle and a key intervention target of ongoing efforts to eradicate malaria. Sexual differentiation is essential for this process, as only sexual parasites, called gametocytes, are infective to the mosquito vector. Gametocyte pro...

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Detalles Bibliográficos
Autores principales: Brancucci, Nicolas M.B., Gerdt, Joseph P., Wang, ChengQi, De Niz, Mariana, Philip, Nisha, Adapa, Swamy R., Zhang, Min, Hitz, Eva, Niederwieser, Igor, Boltryk, Sylwia D., Laffitte, Marie-Claude, Clark, Martha A., Grüring, Christof, Ravel, Deepali, Blancke Soares, Alexandra, Demas, Allison, Bopp, Selina, Rubio-Ruiz, Belén, Conejo-Garcia, Ana, Wirth, Dyann F., Gendaszewska-Darmach, Edyta, Duraisingh, Manoj T., Adams, John H., Voss, Till S., Waters, Andrew P., Jiang, Rays H.Y., Clardy, Jon, Marti, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5733390/
https://www.ncbi.nlm.nih.gov/pubmed/29129376
http://dx.doi.org/10.1016/j.cell.2017.10.020