Positive Feedback Regulation between Transglutaminase 2 and Toll-Like Receptor 4 Signaling in Hepatic Stellate Cells Correlates with Liver Fibrosis Post Schistosoma japonicum Infection

Liver fibrosis induced by Schistosoma japonicum (Sj) infection is characterized by the accumulation of extracellular matrix (ECM). The activated and differentiated hepatic stellate cells (HSCs) are the predominant ECM-producing cell type in the liver. Toll-like receptor (TLR) 4 pathway activation pl...

Descripción completa

Detalles Bibliográficos
Autores principales: Wen, Zhencheng, Ji, Xiaofang, Tang, Juanjuan, Lin, Guiying, Xiao, Linzhuo, Liang, Cuiying, Wang, Manni, Su, Fang, Ferrandon, Dominique, Li, Zi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5733538/
https://www.ncbi.nlm.nih.gov/pubmed/29321784
http://dx.doi.org/10.3389/fimmu.2017.01808

Ejemplares similares

Ejemplares similares