Cargando…

Netrin-1 Prevents Rat Primary Cortical Neurons from Apoptosis via the DCC/ERK Pathway

In the nervous system, Netrin-1 serves as a neural guide, mediating the neuronal development. However, it remains blurred whether Netrin-1 can protect neurons from apoptosis induced by cerebral stroke. In the current study, the cultured rat primary cortical neurons were transfected with Netrin-1-enc...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Jianhao, Du, Houwei, Zhang, Yixian, Chen, Hongbin, Zheng, Mouwei, Lin, Peiqiang, Lan, Quan, Yuan, Qilin, Lai, Yongxing, Pan, Xiaodong, Chen, Ronghua, Liu, Nan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5733550/ https://www.ncbi.nlm.nih.gov/pubmed/29321724 http://dx.doi.org/10.3389/fncel.2017.00387

Ejemplares similares

Netrin-1 Promotes Synaptic Formation and Axonal Regeneration via JNK1/c-Jun Pathway after the Middle Cerebral Artery Occlusion
por: Zheng, Mouwei, et al.
Publicado: (2018)

Restoration of L-OPA1 alleviates acute ischemic stroke injury in rats via inhibiting neuronal apoptosis and preserving mitochondrial function
por: Lai, Yongxing, et al.
Publicado: (2020)

IL-10 produces a dual effect on OGD-induced neuronal apoptosis of cultured cortical neurons via the NF-κB pathway
por: Chen, Hongbin, et al.
Publicado: (2019)

IL-10 Promotes Neurite Outgrowth and Synapse Formation in Cultured Cortical Neurons after the Oxygen-Glucose Deprivation via JAK1/STAT3 Pathway
por: Chen, Hongbin, et al.
Publicado: (2016)

Netrin-1 – DCC Signaling Systems and Age-Related Macular Degeneration
por: SanGiovanni, John Paul, et al.
Publicado: (2015)

IL-10 Protects Neurites in Oxygen-Glucose-Deprived Cortical Neurons through the PI3K/Akt Pathway
por: Lin, Longzai, et al.
Publicado: (2015)

Netrin1/DCC signaling promotes neuronal migration in the dorsal spinal cord
por: Junge, Harald J., et al.
Publicado: (2016)

Effects of treadmill exercise on cerebral angiogenesis and MT1‐MMP expression after cerebral ischemia in rats
por: Tang, Yi, et al.
Publicado: (2018)

The Drosophila Netrin receptor frazzled/DCC functions as an invasive tumor suppressor
por: VanZomeren-Dohm, Adrienne, et al.
Publicado: (2011)

Identification of immune microenvironment subtypes and signature genes for Alzheimer’s disease diagnosis and risk prediction based on explainable machine learning
por: Lai, Yongxing, et al.
Publicado: (2022)

Phosphorylation of DCC by Fyn mediates Netrin-1 signaling in growth cone guidance
por: Meriane, Mayya, et al.
Publicado: (2004)

The netrin receptor DCC focuses invadopodia-driven basement membrane transmigration in vivo
por: Hagedorn, Elliott J., et al.
Publicado: (2013)

Cell invasion through basement membrane: The netrin receptor DCC guides the way
por: Morrissey, Meghan A, et al.
Publicado: (2013)

Egr-1 increases angiogenesis in cartilage via binding Netrin-1 receptor DCC promoter
por: Sheng, Jun, et al.
Publicado: (2018)

The binding of DCC-P3 motif and FAK-FAT domain mediates the initial step of netrin-1/DCC signaling for axon attraction
por: Xu, Shutong, et al.
Publicado: (2018)

The Netrin-1 receptor DCC is a regulator of maladaptive responses to chronic morphine administration
por: Liang, De-Yong, et al.
Publicado: (2014)

Netrins and Frazzled/DCC promote the migration and mesenchymal to epithelial transition of Drosophila midgut cells
por: Pert, Melissa, et al.
Publicado: (2015)

Structural Basis for Draxin-Modulated Axon Guidance and Fasciculation by Netrin-1 through DCC
por: Liu, Ying, et al.
Publicado: (2018)

UNC-6 (netrin) stabilizes oscillatory clustering of the UNC-40 (DCC) receptor to orient polarity
por: Wang, Zheng, et al.
Publicado: (2014)

Targeting netrin‐1/DCC interaction in diffuse large B‐cell and mantle cell lymphomas
por: Broutier, Laura, et al.
Publicado: (2016)

The Netrin-1/DCC guidance system: dopamine pathway maturation and psychiatric disorders emerging in adolescence
por: Vosberg, Daniel E., et al.
Publicado: (2019)

Netrin-1 receptor DCC is required for the contralateral topography of lamina I anterolateral system neurons
por: Bourojeni, Farin B., et al.
Publicado: (2021)

An imbalance of netrin‐1 and DCC during nigral degeneration in experimental models and patients with Parkinson's disease
por: Hua, Ye, et al.
Publicado: (2023)

Netrin‐1 and its receptor DCC modulate survival and death of dopamine neurons and Parkinson’s disease features
por: Jasmin, Mélissa, et al.
Publicado: (2020)

Further confirmation of netrin 1 receptor (DCC) as a depression risk gene via integrations of multi-omics data
por: Li, Hui-Juan, et al.
Publicado: (2020)

Expression and Relationship of Netrin-1, DCC, UNC5B, and VEGF in Villous Tissues of Patients with Delayed Abortion
por: Dong, Fen, et al.
Publicado: (2022)

The Prognostic Value of Deleted in Colorectal Cancer (DCC) Receptor and Serum Netrin-1 in Severe Traumatic Brain Injury
por: Zhang, Yuanda, et al.
Publicado: (2022)

Experimental evidence for UNC-6 (netrin) axon guidance by stochastic fluctuations of intracellular UNC-40 (DCC) outgrowth activity
por: Kulkarni, Gauri, et al.
Publicado: (2013)

The netrin receptor UNC-40/DCC assembles a postsynaptic scaffold and sets the synaptic content of GABA(A) receptors
por: Zhou, Xin, et al.
Publicado: (2020)

The netrin‐1 receptor DCC promotes the survival of a subpopulation of midbrain dopaminergic neurons: Relevance for ageing and Parkinson’s disease
por: Lo, Pik‐Shan, et al.
Publicado: (2022)

Retracted: Expression and Relationship of Netrin-1, DCC, UNC5B, and VEGF in Villous Tissues of Patients with Delayed Abortion
por: Imaging, Contrast Media & Molecular
Publicado: (2023)

Effects of Bone Marrow-Derived Mesenchymal Stem Cells on the Axonal Outgrowth through Activation of PI3K/AKT Signaling in Primary Cortical Neurons Followed Oxygen-Glucose Deprivation Injury
por: Liu, Yong, et al.
Publicado: (2013)

Extracellular Matrix Regulates UNC-6 (Netrin) Axon Guidance by Controlling the Direction of Intracellular UNC-40 (DCC) Outgrowth Activity
por: Yang, Yong, et al.
Publicado: (2014)

Unique Effects of Social Defeat Stress in Adolescent Male Mice on the Netrin-1/DCC Pathway, Prefrontal Cortex Dopamine and Cognition
por: Vassilev, Philip, et al.
Publicado: (2021)

Effects of intra-arterial transplantation of adipose-derived stem cells on the expression of netrin-1 and its receptor DCC in the peri-infarct cortex after experimental stroke
por: Huang, Huan, et al.
Publicado: (2017)

Neuronal Cell Bodies Remotely Regulate Axonal Growth Response to Localized Netrin-1 Treatment via Second Messenger and DCC Dynamics
por: Blasiak, Agata, et al.
Publicado: (2017)

Association Between Steno-Occlusive Middle Cerebral Artery and Basal Ganglia Perivascular Spaces
por: Du, Houwei, et al.
Publicado: (2020)

Netrin-1 suppresses the MEK/ERK pathway and ITGB4 in pancreatic cancer
por: An, Xi-Zhou, et al.
Publicado: (2016)

Total Cerebral Small Vessel Disease Score and Cerebral Bleeding Risk in Patients With Acute Stroke Treated With Intravenous Thrombolysis
por: Du, Houwei, et al.
Publicado: (2022)

Netrin-1/DCC Signaling Differentially Regulates the Migration of Pax7, Nkx6.1, Irx2, Otp, and Otx2 Cell Populations in the Developing Interpeduncular Nucleus
por: García-Guillén, Isabel M., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_1049fhcaoaur70d2g1oprb3nv7