Glyoxals as in vivo RNA structural probes of guanine base-pairing

Elucidation of the folded structures that RNA forms in vivo is vital to understanding its functions. Chemical reagents that modify the Watson–Crick (WC) face of unprotected nucleobases are particularly useful in structure elucidation. Dimethyl sulfate penetrates cell membranes and informs on RNA bas...

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Detalles Bibliográficos
Autores principales: Mitchell, David, Ritchey, Laura E., Park, Hongmarn, Babitzke, Paul, Assmann, Sarah M., Bevilacqua, Philip C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5733565/
https://www.ncbi.nlm.nih.gov/pubmed/29030489
http://dx.doi.org/10.1261/rna.064014.117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5733565/
https://www.ncbi.nlm.nih.gov/pubmed/29030489
http://dx.doi.org/10.1261/rna.064014.117

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