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MicroRNA-155 induction via TNF-α and IFN-γ suppresses expression of programmed death ligand-1 (PD-L1) in human primary cells

Programmed death ligand-1 (PD-L1) is a critical regulator of T cell function contributing to peripheral immune tolerance. Although it has been shown that posttranscriptional regulatory mechanisms control PD-L1 expression in cancer, it remains unknown whether such regulatory loops operate also in non...

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Detalles Bibliográficos
Autores principales:	Yee, Daniel, Shah, Kunal M., Coles, Mark C., Sharp, Tyson V., Lagos, Dimitris
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2017
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5733604/ https://www.ncbi.nlm.nih.gov/pubmed/29066622 http://dx.doi.org/10.1074/jbc.M117.809053

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