Adeno-associated Virus (AAV) Dual Vector Strategies for Gene Therapy Encoding Large Transgenes

The use of adeno-associated viral (AAV) vectors for gene therapy treatments of inherited disorders has accelerated over the past decade with multiple clinical trials ongoing in varying tissue types and new ones initiating every year. These vectors are exhibiting low-immunogenicity across the clinica...

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Detalles Bibliográficos
Autores principales: McClements, Michelle E., MacLaren, Robert E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: YJBM 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5733846/
https://www.ncbi.nlm.nih.gov/pubmed/29259525

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