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CRTH2 antagonists in asthma: current perspectives

Chemoattractant receptor-homologous molecule expressed on T(H)2 cells (CRTH2) binds to prostaglandin D(2). CRTH2 is expressed on various cell types including eosinophils, mast cells, and basophils. CRTH2 and prostaglandin D(2) are involved in allergic inflammation and eosinophil activation. Orally a...

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Detalles Bibliográficos
Autores principales:	Singh, Dave, Ravi, Arjun, Southworth, Thomas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2017
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5733922/ https://www.ncbi.nlm.nih.gov/pubmed/29276415 http://dx.doi.org/10.2147/CPAA.S119295

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