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Anti-angiogenic effects of biotechnological therapies in rheumatic diseases
INTRODUCTION: Angiogenesis plays a key role in the pathogenesis of numerous rheumatic diseases, such as rheumatoid arthritis, psoriatic arthritis, and vasculitides. Therefore, the inhibition of pathological angiogenesis may be considered a useful therapeutical approach in these rheumatic diseases. M...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Dove Medical Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5733924/ https://www.ncbi.nlm.nih.gov/pubmed/29276377 http://dx.doi.org/10.2147/BTT.S143674 |
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author | Cantatore, Francesco Paolo Maruotti, Nicola Corrado, Addolorata Ribatti, Domenico |
author_facet | Cantatore, Francesco Paolo Maruotti, Nicola Corrado, Addolorata Ribatti, Domenico |
author_sort | Cantatore, Francesco Paolo |
collection | PubMed |
description | INTRODUCTION: Angiogenesis plays a key role in the pathogenesis of numerous rheumatic diseases, such as rheumatoid arthritis, psoriatic arthritis, and vasculitides. Therefore, the inhibition of pathological angiogenesis may be considered a useful therapeutical approach in these rheumatic diseases. METHODS: This review article is based on a literature research about the role of biotechnological therapies in angiogenesis inhibition. RESULTS AND CONCLUSIONS: Several evidences have demonstrated a role for biotechnological therapies in angiogenesis inhibition. Nevertheless, further research and clinical trials are needed to better quantify the real impact of biotechnological therapies on pathological angiogenesis. |
format | Online Article Text |
id | pubmed-5733924 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Dove Medical Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-57339242017-12-22 Anti-angiogenic effects of biotechnological therapies in rheumatic diseases Cantatore, Francesco Paolo Maruotti, Nicola Corrado, Addolorata Ribatti, Domenico Biologics Review INTRODUCTION: Angiogenesis plays a key role in the pathogenesis of numerous rheumatic diseases, such as rheumatoid arthritis, psoriatic arthritis, and vasculitides. Therefore, the inhibition of pathological angiogenesis may be considered a useful therapeutical approach in these rheumatic diseases. METHODS: This review article is based on a literature research about the role of biotechnological therapies in angiogenesis inhibition. RESULTS AND CONCLUSIONS: Several evidences have demonstrated a role for biotechnological therapies in angiogenesis inhibition. Nevertheless, further research and clinical trials are needed to better quantify the real impact of biotechnological therapies on pathological angiogenesis. Dove Medical Press 2017-12-14 /pmc/articles/PMC5733924/ /pubmed/29276377 http://dx.doi.org/10.2147/BTT.S143674 Text en © 2017 Cantatore et al. This work is published and licensed by Dove Medical Press Limited The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. |
spellingShingle | Review Cantatore, Francesco Paolo Maruotti, Nicola Corrado, Addolorata Ribatti, Domenico Anti-angiogenic effects of biotechnological therapies in rheumatic diseases |
title | Anti-angiogenic effects of biotechnological therapies in rheumatic diseases |
title_full | Anti-angiogenic effects of biotechnological therapies in rheumatic diseases |
title_fullStr | Anti-angiogenic effects of biotechnological therapies in rheumatic diseases |
title_full_unstemmed | Anti-angiogenic effects of biotechnological therapies in rheumatic diseases |
title_short | Anti-angiogenic effects of biotechnological therapies in rheumatic diseases |
title_sort | anti-angiogenic effects of biotechnological therapies in rheumatic diseases |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5733924/ https://www.ncbi.nlm.nih.gov/pubmed/29276377 http://dx.doi.org/10.2147/BTT.S143674 |
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