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Prostate cancer in renal transplant recipients
As patients with end-stage renal disease are receiving renal allografts at older ages, the number of male renal transplant recipients (RTRs) being diagnosed with prostate cancer (CaP) is increasing. Historically, the literature regarding the management of CaP in RTR's is limited to case reports...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Sociedade Brasileira de Urologia
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5734064/ https://www.ncbi.nlm.nih.gov/pubmed/28338305 http://dx.doi.org/10.1590/S1677-5538.IBJU.2016.0510 |
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author | Sherer, Benjamin A. Warrior, Krishnan Godlewski, Karl Hertl, Martin Olaitan, Oyedolamu Nehra, Ajay Deane, Leslie Allan |
author_facet | Sherer, Benjamin A. Warrior, Krishnan Godlewski, Karl Hertl, Martin Olaitan, Oyedolamu Nehra, Ajay Deane, Leslie Allan |
author_sort | Sherer, Benjamin A. |
collection | PubMed |
description | As patients with end-stage renal disease are receiving renal allografts at older ages, the number of male renal transplant recipients (RTRs) being diagnosed with prostate cancer (CaP) is increasing. Historically, the literature regarding the management of CaP in RTR's is limited to case reports and small case series. To date, there are no standardized guidelines for screening or management of CaP in these complex patients. To better understand the unique characteristics of CaP in the renal transplant population, we performed a literature review of PubMed, without date limitations, using a combination of search terms including prostate cancer, end stage renal disease, renal transplantation, prostate cancer screening, prostate specific antigen kinetics, immuno-suppression, prostatectomy, and radiation therapy. Of special note, teams facilitating the care of these complex patients must carefully and meticulously consider the altered anatomy for surgical and radiotherapeutic planning. Active surveillance, though gaining popularity in the general low risk prostate cancer population, needs further study in this group, as does the management of advance disease. This review provides a comprehensive and contemporary understanding of the incidence, screening measures, risk stratification, and treatment options for CaP in RTRs. |
format | Online Article Text |
id | pubmed-5734064 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Sociedade Brasileira de Urologia |
record_format | MEDLINE/PubMed |
spelling | pubmed-57340642017-12-19 Prostate cancer in renal transplant recipients Sherer, Benjamin A. Warrior, Krishnan Godlewski, Karl Hertl, Martin Olaitan, Oyedolamu Nehra, Ajay Deane, Leslie Allan Int Braz J Urol Review Article As patients with end-stage renal disease are receiving renal allografts at older ages, the number of male renal transplant recipients (RTRs) being diagnosed with prostate cancer (CaP) is increasing. Historically, the literature regarding the management of CaP in RTR's is limited to case reports and small case series. To date, there are no standardized guidelines for screening or management of CaP in these complex patients. To better understand the unique characteristics of CaP in the renal transplant population, we performed a literature review of PubMed, without date limitations, using a combination of search terms including prostate cancer, end stage renal disease, renal transplantation, prostate cancer screening, prostate specific antigen kinetics, immuno-suppression, prostatectomy, and radiation therapy. Of special note, teams facilitating the care of these complex patients must carefully and meticulously consider the altered anatomy for surgical and radiotherapeutic planning. Active surveillance, though gaining popularity in the general low risk prostate cancer population, needs further study in this group, as does the management of advance disease. This review provides a comprehensive and contemporary understanding of the incidence, screening measures, risk stratification, and treatment options for CaP in RTRs. Sociedade Brasileira de Urologia 2017 /pmc/articles/PMC5734064/ /pubmed/28338305 http://dx.doi.org/10.1590/S1677-5538.IBJU.2016.0510 Text en https://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Sherer, Benjamin A. Warrior, Krishnan Godlewski, Karl Hertl, Martin Olaitan, Oyedolamu Nehra, Ajay Deane, Leslie Allan Prostate cancer in renal transplant recipients |
title | Prostate cancer in renal transplant recipients |
title_full | Prostate cancer in renal transplant recipients |
title_fullStr | Prostate cancer in renal transplant recipients |
title_full_unstemmed | Prostate cancer in renal transplant recipients |
title_short | Prostate cancer in renal transplant recipients |
title_sort | prostate cancer in renal transplant recipients |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5734064/ https://www.ncbi.nlm.nih.gov/pubmed/28338305 http://dx.doi.org/10.1590/S1677-5538.IBJU.2016.0510 |
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