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Targeted simplification versus antipseudomonal broad-spectrum beta-lactams in patients with bloodstream infections due to Enterobacteriaceae (SIMPLIFY): a study protocol for a multicentre, open-label, phase III randomised, controlled, non-inferiority clinical trial

INTRODUCTION: Within the context of antimicrobial stewardship programmes, de-escalation of antimicrobial therapy is one of the proposed strategies for reducing the unnecessary use of broad-spectrum antibiotics (BSA). The empirical treatment of nosocomial and some healthcare-associated bloodstream in...

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Detalles Bibliográficos
Autores principales:	López-Cortés, Luis Eduardo, Rosso-Fernández, Clara, Núñez-Núñez, María, Lavín-Alconero, Lucía, Bravo-Ferrer, José, Barriga, Ángel, Delgado, Mercedes, Lupión, Carmen, Retamar, Pilar, Rodríguez-Baño, Jesús
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2017
Materias:	Infectious Diseases
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5734512/ https://www.ncbi.nlm.nih.gov/pubmed/28601833 http://dx.doi.org/10.1136/bmjopen-2016-015439

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