Cargando…
An automated high-throughput system for phenotypic screening of chemical libraries on C. elegans and parasitic nematodes
Parasitic nematodes infect hundreds of millions of people and farmed livestock. Further, plant parasitic nematodes result in major crop damage. The pipeline of therapeutic compounds is limited and parasite resistance to the existing anthelmintic compounds is a global threat. We have developed an INV...
Autores principales: | Partridge, Frederick A., Brown, Anwen E., Buckingham, Steven D., Willis, Nicky J., Wynne, Graham M., Forman, Ruth, Else, Kathryn J., Morrison, Alison A., Matthews, Jacqueline B., Russell, Angela J., Lomas, David A., Sattelle, David B. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5734697/ https://www.ncbi.nlm.nih.gov/pubmed/29223747 http://dx.doi.org/10.1016/j.ijpddr.2017.11.004 |
Ejemplares similares
-
Automated, high-throughput, motility analysis in Caenorhabditiselegans and parasitic nematodes: Applications in the search for new anthelmintics
por: Buckingham, Steven D., et al.
Publicado: (2014) -
2,4-Diaminothieno[3,2-d]pyrimidines, a new class of anthelmintic with activity against adult and egg stages of whipworm
por: Partridge, Frederick A., et al.
Publicado: (2018) -
Fast, automated measurement of nematode swimming (thrashing) without morphometry
por: Buckingham, Steven D, et al.
Publicado: (2009) -
The cys-loop ligand-gated ion channel gene superfamily of the nematode, Caenorhabditis elegans
por: Jones, Andrew K., et al.
Publicado: (2008) -
Anthelmintic drug discovery: target identification, screening methods and the role of open science
por: Partridge, Frederick A, et al.
Publicado: (2020)