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New roles for nuclear EGFR in regulating the stability and translation of mRNAs associated with VEGF signaling
Cell membrane-associated epidermal growth factor receptor (EGFR) translocates into a perinuclear/nuclear location upon stimulation, where it complexes with mRNAs. Treatment with radiation and cisplatin decreases the amounts of mRNAs present within this complex. Gene array analyses of mRNAs in comple...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5734708/ https://www.ncbi.nlm.nih.gov/pubmed/29253018 http://dx.doi.org/10.1371/journal.pone.0189087 |