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New roles for nuclear EGFR in regulating the stability and translation of mRNAs associated with VEGF signaling

Cell membrane-associated epidermal growth factor receptor (EGFR) translocates into a perinuclear/nuclear location upon stimulation, where it complexes with mRNAs. Treatment with radiation and cisplatin decreases the amounts of mRNAs present within this complex. Gene array analyses of mRNAs in comple...

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Detalles Bibliográficos
Autores principales: Dittmann, Klaus, Mayer, Claus, Czemmel, Stefan, Huber, Stephan M., Rodemann, H. Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5734708/
https://www.ncbi.nlm.nih.gov/pubmed/29253018
http://dx.doi.org/10.1371/journal.pone.0189087