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Effects of GABA(C)R and mGluR1 antagonists on contrast response functions of Sprague-Dawley and P23H rat retinal ganglion cells

The GABA(C)R antagonist TPMPA and the mGluR1 antagonist JNJ16259685 have been shown previously to alter the sensitivity of retinal ganglion cells (RGCs) in the Sprague-Dawley (SD) rat and P23H rat (animal model of retinitis pigmentosa) to brief flashes of light. In order to better understand the eff...

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Detalles Bibliográficos
Autor principal: Jensen, Ralph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5734767/
https://www.ncbi.nlm.nih.gov/pubmed/29253887
http://dx.doi.org/10.1371/journal.pone.0189980