Cargando…
Radiation enhanced the local and distant anti-tumor efficacy in dual immune checkpoint blockade therapy in osteosarcoma
Radiation therapy has been long utilized as localized cancer treatment. Recent studies have also demonstrated that it has a distant effect by the enhanced immunity, but it rarely occurs. The purpose of this study was to investigate whether X-ray irradiation combined with anti-PD-L1 and anti-CTLA-4 a...
Autores principales: | Takahashi, Yutaka, Yasui, Tomohiro, Tamari, Keisuke, Minami, Kazumasa, Otani, Keisuke, Isohashi, Fumiaki, Seo, Yuji, Kambe, Ryosuke, Koizumi, Masahiko, Ogawa, Kazuhiko |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5734786/ https://www.ncbi.nlm.nih.gov/pubmed/29253865 http://dx.doi.org/10.1371/journal.pone.0189697 |
Ejemplares similares
-
Carbon ion irradiation enhances the antitumor efficacy of dual immune checkpoint blockade therapy both for local and distant sites in murine osteosarcoma
por: Takahashi, Yutaka, et al.
Publicado: (2019) -
Radiation Dose Escalation Is Crucial in Anti-CTLA-4 Antibody Therapy to Enhance Local and Distant Antitumor Effect in Murine Osteosarcoma
por: Takenaka, Wataru, et al.
Publicado: (2020) -
Radiation therapy enhances systemic antitumor efficacy in PD-L1 therapy regardless of sequence of radiation in murine osteosarcoma
por: Katsuki, Shohei, et al.
Publicado: (2022) -
High Dose Local Photon Irradiation Is Crucial in Anti-CTLA-4 Antibody Therapy to Enhance the Abscopal Response in a Murine Pancreatic Carcinoma Model
por: Yamamoto, Junya, et al.
Publicado: (2022) -
Chk1 suppression leads to a reduction in the enhanced radiation-induced invasive capability on breast cancer cells
por: Adachi, Takanori, et al.
Publicado: (2021)