Cargando…
Relationship between Serum 25-hydroxy-vitamin D Concentration and Risk of Metabolic Syndrome in Patients with Fatty Liver
BACKGROUND: The vitamin D deficiency rate in Koreans is still high and dietary intake is insufficient. The purpose of this study was to provide basic data for the management of metabolic syndrome (MetS) by analyzing the effect of vitamin D levels on the MetS in patients with fatty liver. METHODS: We...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Society for Bone and Mineral Research
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5734947/ https://www.ncbi.nlm.nih.gov/pubmed/29259961 http://dx.doi.org/10.11005/jbm.2017.24.4.223 |
_version_ | 1783287115608489984 |
---|---|
author | Lim, Hee-Sook Kim, Tae-Hee Lee, Hae-Hyeog Kim, Soon-Kyung Lee, Bora Park, Yoon-Hyung |
author_facet | Lim, Hee-Sook Kim, Tae-Hee Lee, Hae-Hyeog Kim, Soon-Kyung Lee, Bora Park, Yoon-Hyung |
author_sort | Lim, Hee-Sook |
collection | PubMed |
description | BACKGROUND: The vitamin D deficiency rate in Koreans is still high and dietary intake is insufficient. The purpose of this study was to provide basic data for the management of metabolic syndrome (MetS) by analyzing the effect of vitamin D levels on the MetS in patients with fatty liver. METHODS: We analyzed the MetS ratio and serum 25-hydroxy-vitamin D (25[OH]D) concentration in 151 adults diagnosed with fatty liver by using obesity index and blood profiles. We collected data on demographic factors, nutrient intake, and lifestyle habits. RESULTS: The mean 25(OH)D concentration of all subjects was 14 ng/mL and the insufficiency and deficiency rates were 40.4% and 29.8%. The proportion of MetS was 38.4% and the mean 25(OH)D level of MetS group was 12.1 ng/mL. Low-density lipoprotein cholesterol, triglyceride, and blood glucose were higher in the MetS group than in the normal group, and the waist circumference of the male was significantly higher than that of the normal group. The results showed that the lower the vitamin D concentration, the higher the risk of MetS (odds ratio, 1.47, 95% confidence interval, 0.98–2.81; P=0.043). CONCLUSIONS: These results suggest that serum 25(OH)D levels may be a risk factor for MetS in patients with fatty liver. |
format | Online Article Text |
id | pubmed-5734947 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | The Korean Society for Bone and Mineral Research |
record_format | MEDLINE/PubMed |
spelling | pubmed-57349472017-12-19 Relationship between Serum 25-hydroxy-vitamin D Concentration and Risk of Metabolic Syndrome in Patients with Fatty Liver Lim, Hee-Sook Kim, Tae-Hee Lee, Hae-Hyeog Kim, Soon-Kyung Lee, Bora Park, Yoon-Hyung J Bone Metab Original Article BACKGROUND: The vitamin D deficiency rate in Koreans is still high and dietary intake is insufficient. The purpose of this study was to provide basic data for the management of metabolic syndrome (MetS) by analyzing the effect of vitamin D levels on the MetS in patients with fatty liver. METHODS: We analyzed the MetS ratio and serum 25-hydroxy-vitamin D (25[OH]D) concentration in 151 adults diagnosed with fatty liver by using obesity index and blood profiles. We collected data on demographic factors, nutrient intake, and lifestyle habits. RESULTS: The mean 25(OH)D concentration of all subjects was 14 ng/mL and the insufficiency and deficiency rates were 40.4% and 29.8%. The proportion of MetS was 38.4% and the mean 25(OH)D level of MetS group was 12.1 ng/mL. Low-density lipoprotein cholesterol, triglyceride, and blood glucose were higher in the MetS group than in the normal group, and the waist circumference of the male was significantly higher than that of the normal group. The results showed that the lower the vitamin D concentration, the higher the risk of MetS (odds ratio, 1.47, 95% confidence interval, 0.98–2.81; P=0.043). CONCLUSIONS: These results suggest that serum 25(OH)D levels may be a risk factor for MetS in patients with fatty liver. The Korean Society for Bone and Mineral Research 2017-11 2017-11-30 /pmc/articles/PMC5734947/ /pubmed/29259961 http://dx.doi.org/10.11005/jbm.2017.24.4.223 Text en Copyright © 2017 The Korean Society for Bone and Mineral Research http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Lim, Hee-Sook Kim, Tae-Hee Lee, Hae-Hyeog Kim, Soon-Kyung Lee, Bora Park, Yoon-Hyung Relationship between Serum 25-hydroxy-vitamin D Concentration and Risk of Metabolic Syndrome in Patients with Fatty Liver |
title | Relationship between Serum 25-hydroxy-vitamin D Concentration and Risk of Metabolic Syndrome in Patients with Fatty Liver |
title_full | Relationship between Serum 25-hydroxy-vitamin D Concentration and Risk of Metabolic Syndrome in Patients with Fatty Liver |
title_fullStr | Relationship between Serum 25-hydroxy-vitamin D Concentration and Risk of Metabolic Syndrome in Patients with Fatty Liver |
title_full_unstemmed | Relationship between Serum 25-hydroxy-vitamin D Concentration and Risk of Metabolic Syndrome in Patients with Fatty Liver |
title_short | Relationship between Serum 25-hydroxy-vitamin D Concentration and Risk of Metabolic Syndrome in Patients with Fatty Liver |
title_sort | relationship between serum 25-hydroxy-vitamin d concentration and risk of metabolic syndrome in patients with fatty liver |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5734947/ https://www.ncbi.nlm.nih.gov/pubmed/29259961 http://dx.doi.org/10.11005/jbm.2017.24.4.223 |
work_keys_str_mv | AT limheesook relationshipbetweenserum25hydroxyvitamindconcentrationandriskofmetabolicsyndromeinpatientswithfattyliver AT kimtaehee relationshipbetweenserum25hydroxyvitamindconcentrationandriskofmetabolicsyndromeinpatientswithfattyliver AT leehaehyeog relationshipbetweenserum25hydroxyvitamindconcentrationandriskofmetabolicsyndromeinpatientswithfattyliver AT kimsoonkyung relationshipbetweenserum25hydroxyvitamindconcentrationandriskofmetabolicsyndromeinpatientswithfattyliver AT leebora relationshipbetweenserum25hydroxyvitamindconcentrationandriskofmetabolicsyndromeinpatientswithfattyliver AT parkyoonhyung relationshipbetweenserum25hydroxyvitamindconcentrationandriskofmetabolicsyndromeinpatientswithfattyliver |