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Central European Woolly Mammoth Population Dynamics: Insights from Late Pleistocene Mitochondrial Genomes
The population dynamics of the Pleistocene woolly mammoth (Mammuthus primigenius) has been the subject of intensive palaeogenetic research. Although a large number of mitochondrial genomes across Eurasia have been reconstructed, the available data remains geographically sparse and mostly focused on...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5735091/ https://www.ncbi.nlm.nih.gov/pubmed/29255197 http://dx.doi.org/10.1038/s41598-017-17723-1 |
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author | Fellows Yates, James A. Drucker, Dorothée G. Reiter, Ella Heumos, Simon Welker, Frido Münzel, Susanne C. Wojtal, Piotr Lázničková-Galetová, Martina Conard, Nicholas J. Herbig, Alexander Bocherens, Hervé Krause, Johannes |
author_facet | Fellows Yates, James A. Drucker, Dorothée G. Reiter, Ella Heumos, Simon Welker, Frido Münzel, Susanne C. Wojtal, Piotr Lázničková-Galetová, Martina Conard, Nicholas J. Herbig, Alexander Bocherens, Hervé Krause, Johannes |
author_sort | Fellows Yates, James A. |
collection | PubMed |
description | The population dynamics of the Pleistocene woolly mammoth (Mammuthus primigenius) has been the subject of intensive palaeogenetic research. Although a large number of mitochondrial genomes across Eurasia have been reconstructed, the available data remains geographically sparse and mostly focused on eastern Eurasia. Thus, population dynamics in other regions have not been extensively investigated. Here, we use a multi-method approach utilising proteomic, stable isotope and genetic techniques to identify and generate twenty woolly mammoth mitochondrial genomes, and associated dietary stable isotopic data, from highly fragmentary Late Pleistocene material from central Europe. We begin to address region-specific questions regarding central European woolly mammoth populations, highlighting parallels with a previous replacement event in eastern Eurasia ten thousand years earlier. A high number of shared derived mutations between woolly mammoth mitochondrial clades are identified, questioning previous phylogenetic analysis and thus emphasizing the need for nuclear DNA studies to explicate the increasingly complex genetic history of the woolly mammoth. |
format | Online Article Text |
id | pubmed-5735091 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-57350912017-12-21 Central European Woolly Mammoth Population Dynamics: Insights from Late Pleistocene Mitochondrial Genomes Fellows Yates, James A. Drucker, Dorothée G. Reiter, Ella Heumos, Simon Welker, Frido Münzel, Susanne C. Wojtal, Piotr Lázničková-Galetová, Martina Conard, Nicholas J. Herbig, Alexander Bocherens, Hervé Krause, Johannes Sci Rep Article The population dynamics of the Pleistocene woolly mammoth (Mammuthus primigenius) has been the subject of intensive palaeogenetic research. Although a large number of mitochondrial genomes across Eurasia have been reconstructed, the available data remains geographically sparse and mostly focused on eastern Eurasia. Thus, population dynamics in other regions have not been extensively investigated. Here, we use a multi-method approach utilising proteomic, stable isotope and genetic techniques to identify and generate twenty woolly mammoth mitochondrial genomes, and associated dietary stable isotopic data, from highly fragmentary Late Pleistocene material from central Europe. We begin to address region-specific questions regarding central European woolly mammoth populations, highlighting parallels with a previous replacement event in eastern Eurasia ten thousand years earlier. A high number of shared derived mutations between woolly mammoth mitochondrial clades are identified, questioning previous phylogenetic analysis and thus emphasizing the need for nuclear DNA studies to explicate the increasingly complex genetic history of the woolly mammoth. Nature Publishing Group UK 2017-12-18 /pmc/articles/PMC5735091/ /pubmed/29255197 http://dx.doi.org/10.1038/s41598-017-17723-1 Text en © The Author(s) 2017 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article Fellows Yates, James A. Drucker, Dorothée G. Reiter, Ella Heumos, Simon Welker, Frido Münzel, Susanne C. Wojtal, Piotr Lázničková-Galetová, Martina Conard, Nicholas J. Herbig, Alexander Bocherens, Hervé Krause, Johannes Central European Woolly Mammoth Population Dynamics: Insights from Late Pleistocene Mitochondrial Genomes |
title | Central European Woolly Mammoth Population Dynamics: Insights from Late Pleistocene Mitochondrial Genomes |
title_full | Central European Woolly Mammoth Population Dynamics: Insights from Late Pleistocene Mitochondrial Genomes |
title_fullStr | Central European Woolly Mammoth Population Dynamics: Insights from Late Pleistocene Mitochondrial Genomes |
title_full_unstemmed | Central European Woolly Mammoth Population Dynamics: Insights from Late Pleistocene Mitochondrial Genomes |
title_short | Central European Woolly Mammoth Population Dynamics: Insights from Late Pleistocene Mitochondrial Genomes |
title_sort | central european woolly mammoth population dynamics: insights from late pleistocene mitochondrial genomes |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5735091/ https://www.ncbi.nlm.nih.gov/pubmed/29255197 http://dx.doi.org/10.1038/s41598-017-17723-1 |
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