α-Asarone Attenuates Cognitive Deficit in a Pilocarpine-Induced Status Epilepticus Rat Model via a Decrease in the Nuclear Factor-κB Activation and Reduction in Microglia Neuroinflammation

BACKGROUND: Temporal lobe epilepsy (TLE) is one of the most drug-resistant types of epilepsy with about 80% of TLE patients falling into this category. Increasing evidence suggests that neuroinflammation, which has a critical role in the epileptogenesis of TLE, is associated with microglial activati...

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Detalles Bibliográficos
Autores principales: Liu, Hui-juan, Lai, Xin, Xu, Yan, Miao, Jing-kun, Li, Chun, Liu, Jing-ying, Hua, Yuan-yuan, Ma, Qian, Chen, Qixiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5735142/
https://www.ncbi.nlm.nih.gov/pubmed/29312110
http://dx.doi.org/10.3389/fneur.2017.00661

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