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Usp9x Promotes Survival in Human Pancreatic Cancer and Its Inhibition Suppresses Pancreatic Ductal Adenocarcinoma In Vivo Tumor Growth()
Usp9x has emerged as a potential therapeutic target in some hematologic malignancies and a broad range of solid tumors including brain, breast, and prostate. To examine Usp9x tumorigenicity and consequence of Usp9x inhibition in human pancreatic tumor models, we carried out gain- and loss-of-functio...
Autores principales: | Pal, Anupama, Dziubinski, Michele, Di Magliano, Marina Pasca, Simeone, Diane M., Owens, Scott, Thomas, Dafydd, Peterson, Luke, Potu, Harish, Talpaz, Moshe, Donato, Nicholas J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Neoplasia Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5735260/ https://www.ncbi.nlm.nih.gov/pubmed/29248719 http://dx.doi.org/10.1016/j.neo.2017.11.007 |
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