Short-term sustained hyperglycaemia fosters an archetypal senescence-associated secretory phenotype in endothelial cells and macrophages

Diabetic status is characterized by chronic low-grade inflammation and an increased burden of senescent cells. Recently, the senescence-associated secretory phenotype (SASP) has been suggested as a possible source of inflammatory factors in obesity-induced type 2 diabetes. However, while senescence...

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Detalles Bibliográficos
Autores principales: Prattichizzo, Francesco, De Nigris, Valeria, Mancuso, Elettra, Spiga, Rosangela, Giuliani, Angelica, Matacchione, Giulia, Lazzarini, Raffaella, Marcheselli, Fiorella, Recchioni, Rina, Testa, Roberto, La Sala, Lucia, Rippo, Maria Rita, Procopio, Antonio Domenico, Olivieri, Fabiola, Ceriello, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5735298/
https://www.ncbi.nlm.nih.gov/pubmed/29253812
http://dx.doi.org/10.1016/j.redox.2017.12.001

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