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Mitofusin 2 Promotes Apoptosis of CD4(+) T Cells by Inhibiting Autophagy in Sepsis

Apoptosis of CD4(+) T cells is a primary pathophysiological mechanism of immune dysfunction in the pathogenesis of sepsis. Mitofusin 2 (Mfn2), an integral mitochondrial outer membrane protein, has been confirmed to be associated with cellular metabolism, proliferation, and apoptosis. The function of...

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Detalles Bibliográficos
Autores principales:	Ying, Lan, Zhao, Guang-Ju, Wu, You, Ke, He-Liang, Hong, Guang-Liang, Zhang, Hui, Dong, Ning, Wu, Yao, Yao, Yong-Ming, Lu, Zhong-Qiu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5735308/ https://www.ncbi.nlm.nih.gov/pubmed/29358849 http://dx.doi.org/10.1155/2017/4926205

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