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Synthesis of Poly-Ubiquitin Chains Using a Bifunctional Ubiquitin Monomer
[Image: see text] An optimized large scale and highly reproducible route to orthogonally protected γ-thiolysine is reported. Its utility in the synthesis of bifunctional ubiquitin monomers is demonstrated. These ubiquitin synthons are employed in polymerization reactions giving access to synthetic p...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5735377/ https://www.ncbi.nlm.nih.gov/pubmed/29172548 http://dx.doi.org/10.1021/acs.orglett.7b03085 |