Production of fluorescent and cytotoxic K28 killer toxin variants through high cell density fermentation of recombinant Pichia pastoris

BACKGROUND: Virus infected killer strains of the baker’s yeast Saccharomyces cerevisiae secrete protein toxins such as K28, K1, K2 and Klus which are lethal to sensitive yeast strains of the same or related species. K28 is somewhat unique as it represents an α/β heterodimeric protein of the A/B toxi...

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Detalles Bibliográficos
Autores principales: Giesselmann, Esther, Becker, Björn, Schmitt, Manfred J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5735513/
https://www.ncbi.nlm.nih.gov/pubmed/29258515
http://dx.doi.org/10.1186/s12934-017-0844-0

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