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Hmox1 Deficiency Sensitizes Mice to Peroxynitrite Formation and Diabetic Glomerular Microvascular Injuries

OBJECTIVE: Indirect evidence suggests a role for heme oxygenase-1 (HO-1) in limiting diabetic vasculopathy. The goal of this study was to assess the role of HO-1 in the development of microvascular lesions within glomeruli during diabetes mellitus using a mouse model with specific alteration of the...

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Detalles Bibliográficos
Autores principales:	Lenoir, Olivia, Gaillard, François, Lazareth, Hélène, Robin, Blaise, Tharaux, Pierre-Louis
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5735626/ https://www.ncbi.nlm.nih.gov/pubmed/29359167 http://dx.doi.org/10.1155/2017/9603924

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