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The rs738409 polymorphism of the PNPLA3 gene is associated with hepatic steatosis and fibrosis in Brazilian patients with chronic hepatitis C

BACKGROUND: Prospective studies have shown that 80% of acute hepatitis C virus (HCV) cases progress to chronic infection; approximately 10-20% of patients with these conditions will develop liver cirrhosis within 2 to 3 decades, and 1-5% will develop liver cancer. Some studies have indicated that th...

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Detalles Bibliográficos
Autores principales: Manchiero, Caroline, Nunes, Arielle Karen da Silva, Magri, Mariana Carvalheiro, Dantas, Bianca Peixoto, Mazza, Celso Carmo, Barone, Antonio Alci, Tengan, Fátima Mitiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5735770/
https://www.ncbi.nlm.nih.gov/pubmed/29258449
http://dx.doi.org/10.1186/s12879-017-2887-6